Texting to Prevent Tranplanted Liver Rejection

A recent study shows that text reminders improves adherence and outcomes in teens

WESTFIELD, NJ [April 28, 2010] Non-adherence, or the failure to follow medical advice, is the most important cause of organ rejection in long-term transplant survivors. Teenagers are at particularly high risk. Studies have shown that more than half of all teenage liver transplant recipients are non-adherent, and they are four times more likely than adult patients to take their medications at the wrong time or to forget to take them.

A study published in Pediatrics in November 2009, showed that liver transplant recipients who received text reminders were more likely to take their anti-rejection medications. The study was conducted by physicians at Department of Pediatrics and the Recanati Miller Transplant Institute at Mount Sinai Hospital and at the Department of Psychology, Fordham University.

Forty-one patients were enrolled. The median age of participants was 15 years and the median age at the time of transplantation was 2 years. During this year-long study, the number of acute cellular rejection episodes decreased from 12 to 2 (P=0.02), regardless of the number of immunosuppressant medications taken or the person who actually administered the medication. The team reported that they observed significant improvement (P<0.005) in medication adherence and a reduction in rejection episodes with text message reminders for pediatric recipients of liver transplants.

"Teens are texting constantly, in fact, seven times more often than they are on the phone, making texting a key driver of medication adherence," said Amy J. Yoffie, CEO at iReminder, a healthcare company that specializes in medical messaging programs. "But they have to feel in control, which is why iReminder's technology lets teens decide at what time they want to be reminded. Parents like it because they are notified if their teenager has not complied with the reminder."

About iReminder
iReminder is a healthcare technology company focused on increasing medication compliance. Marketed to companies in the healthcare sector, iReminder's products include: Compliance for Life for dosing, refill and appointment reminders; MedTrigger for risk management (REMS) programs; and Global e-Trials for multi-country and multilingual communications with patients in clinical trials worldwide. Reminders and messages are delivered by phone, email, SMS text and smart phone in the U.S. and internationally in any language and alphabet. For more information, visit
iReminder.com or call 877-326-3293.

Drive Adherence through Texting

Teens are texting constantly, in fact, seven times more often than they are on the phone, making texting a key driver of medication adherence."